Iopamidol and metrizamide for myelography: prospective double-blind clinical trial
نویسندگان
چکیده
منابع مشابه
Clinical comparison of metrizamide and iopamidol for myelography.
A double-blind parallel comparison of iopamidol and metrizamide for myelography was performed in 36 patients. Sixteen adverse reactions were noted in 10 patients who received metrizamide. Six adverse reactions were reported in five patients who received iopamidol. There was no appreciable difference in the radiographic opacification.
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Lumbar myelography was performed in 50 patients; 25 received iohexol (an investigational aqueous contrast agent) and 25 received metrizamide. The two media produced radiographs of equal quality. However, iohexol is stable in solution, while metrizamide is not. Further, markedly less morbidity resulted from iohexol. These features indicate that iohexol may be superior to metrizamide as a contras...
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Cervical myelography was performed by lateral C1-C2 puncture in 60 patients. Thirty patients received iohexol (an investigational aqueous contrast agent) and 30 received metrizamide in order to provide a prospective, randomized, double-blind trial comparing these contrast media. The two media produced radiographs of equal quality. Contrast-related morbidity was suffered by four patients (13%) i...
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One hundred myelographies with iopamidol and 100 with metrizamide were performed in order to compare the side effects of the two contrast media after injection into the spinal subarachnoid space. All patients were observed for a follow-up period of at least 4 days. The most frequently observed side effect, headache, was more common, of longer duration, and more severe with the use of metrizamid...
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Within 20 months 145 ascending thoracocervical myelographies and 155 lumbar myelographies with the nonionic water-soluble contrast medium iopamidol were performed. The iodine concentration given was 250 mg I/ml or 200 mg I/ml respectively. The total iodine never exceeded 2.5 g (8-10 ml). Image quality was assessed in terms of diagnostic value having experience of more than 1,000 myelographies u...
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ژورنال
عنوان ژورنال: American Journal of Roentgenology
سال: 1984
ISSN: 0361-803X,1546-3141
DOI: 10.2214/ajr.143.4.869